New Step by Step Map For CX-5461
Graphical presentation of CX-5461-mediated activation from the cytosolic DNA sensing pathway. cGAS binding to your cytosolic DNA activates the secondary messenger 2,three-cGAMP applying cGAS as a catalyst. Activated STING buds from the ER going for the perinuclear Golgi, exactly where it can be palmitoylated.In the meantime, to guarantee continued